How have different creative teams (like Steve Ditko and Stan Lee) shaped Spider-Man's friendships in the comics?

Different writers and artists have brought unique perspectives to Spider-Man's friendships. Steve Ditko, a key creative force in the early years, emphasized the isolation and loneliness of the hero, highlighting the importance of his few close connections. Later writers, like Stan Lee and more recently, J. Michael Straczynski, have explored the complexities of these relationships with greater depth, showcasing the emotional toll of being Spider-Man and the value of having trusted friends.